Organization and function of the visual system in healthy animal models and models of disease.

Faculty Profile…

My lab focuses on conditions of brain development and injury where a treatment does not yet exist. We are creating new models of complex neurological disorders, developing cellular and molecular tools that enable precise manipulation…

Our work is in basic and clinical vascular neurobiology, with a primary focus on mechanistic studies of stroke and cerebrovascular disease. We perform animal and cell culture studies, clinical investigations, and population studies.

Faculty Link…

John H. Weiss, MD, Ph.D., ProfessorDr. Weiss received his BS, MS, MD, and Ph.D. (in Neuroscience) degrees as well as residency training in Neurology at Stanford University, and came to UC Irvine in 1991. The…

We are studying how early life experiences, including adversity/stress or seizures influences that maturation of our brain. Answering this question requires distinct perspectives and levels of analyses:a. Molecular/ cellular. we study epigenetic changes in specific…

Our project focuses on the development of highly efficient and reproducible brain organoid methods to investigate the origins of neural circuits and model neurodevelopmental disorders. We have contributed to set up cortical-subcortical fused-organoids to identify…

My laboratory focuses on a combination of discovery biology and identifying translational neuroscience strategies for spinal cord injury and central nervous system disease. Pre-clinical and translational work from my lab directly supported an IND filing…

Throughout the brain, neurons communicate with each other through synapses, where neuronal specializations—presynaptic terminals, equipped with neurotransmitter release machineries, and postsynapses, containing neurotransmitter receptors—are connected by a narrow synaptic cleft. The correct positioning of elements…

The Igarashi lab investigates brain circuits for memory in Health and Disease

The scent of your parents’ signature gingerbread can trigger sweet childhood memories and will vividly remind you of past events. Impairments of memory function…

Dr. Lisa Flanagan is a member of the Department of Neurology at the University of California, Irvine, with joint appointments in Biomedical Engineering and Anatomy and Neurobiology. Dr. Flanagan’s research program combines the fields of…